Lots will include a selection of British Commonwealth stamps, mostly unmounted, with a book price of AU$1,200.
These include Antigua QEII 1953 pictorials, a block of six Australia 1971-73 7c with jumped perforations and assorted Bermuda, Barbados, Canadian and Indian stamps.
Elsewhere, a 9d violet Watermark Inverted BW #25a - of which only around 24 used examples are known - will be up for sale.
Although slightly perforated and a little aged, hopes are high for the stamp estimated at AU$1,000 - one sold for US$2,645 in February 2007.
Higher-priced lots include a bock of 12 1862-67 1d orange-vermilion SG22 stamps with no watermark, going under the hammer with a book price of AU$4,000.
Elsewhere, a 1d reddish brown horizontal block of four 1880 Surcharge 'Half-penny' stamps are hoped to bring AU$2,500 due to their rarity and desirability.
(A rejoined block of two pairs sold for an impressive AU$2,875 at a 2004 Sydney auction)
The sale will be held at the Prestige Philately Showroom in Belgrave, Melbourne. Pre-sale viewings will be held between Monday August 31 and Friday September 4, 10am-6pm.