A fine example of Banksy's Love is in the Air image is up for grabs at Bonhams London on June 27.
The £100,000 ($160,000)-estimated piece is the highlight of the auction house's Contemporary Art and Design sale.
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Signed and dated in 2006, the spray paint on canvas was acquired by the consignor directly from the secretive street artist in the same year - a factor which will no doubt enhance its value.
Alan Montgomery, a specialist in contemporary art at Bonhams, commented: "Prices for spray paint canvases by Banksy in our recent auctions demonstrate that his works are more popular than ever with high-profile art collectors, reflecting the continuing fascination with his art amongst the public as a whole.
"This Love is in the Air is one of his best-known images, and we expect significant interest in this lot."
Banksy's Slave Labour mural, controversially removed from a London street, sold for more than £750,000 ($1.1m) earlier this month, according to Bloomberg.
The Banksy word record stands at $1.9m, achieved by his Keep It Spotless at a Sotheby's auction in December 2008.
The auction will also feature a Damien Hirst spin painting, valued at £40,000 ($62,000), as well as a Tracey Emin sculpture of her cat, Docket, valued at £3,000 ($4,700).
Two Gilbert and George postcards will sell with £8,000 ($12,000) and £15,000 ($23,000) high estimates, respectively.
You can view our wide range of art for sale here.